反应详情

A mixture of 7-ethyl-1,2,4-triazolo[1,5-a]pyrimidine (10.5 g), N-bromosuccinimide (12.63 g), dibenzoylperoxide (0.3 g) and tetrachloromethane (270 ml) was heated under reflux for 5 hours with stirring. The mixture was filtered and a crude product was obtained by evaporation of the solvent from the filtrate. This was purified by recrystallisation from tetrachloromethane to give 7-(1-bromoethyl)-1,2,4-triazolo[1,5-a]pyrimidine. Yield 10.8 g.

1. temperaturewas heated
2. temperatureunder reflux for 5 hours
3. filtrationThe mixture was filtered
4. customa crude product was obtained by evaporation of the solvent from the filtrate
5. customThis was purified by recrystallisation from tetrachloromethane