HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Tert.butoxycarbonyl-4-[4-(2-oxazolin-2-yl)benzylidene]piperidine → 1-Tert.butoxycarbonyl-4-[4-(2-oxazolin-2-yl)benzyl]piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Tert.butoxycarbonyl-4-[4-(2-oxazolin-2-yl)benzylidene]piperidine | HCID 19372666 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 1-Tert.butoxycarbonyl-4-[4-(2-oxazolin-2-yl)benzyl]piperidine | HCID 57257687 | — |
Reaction Steps
2.4 g (7 mmool) of 1-tert.butoxycarbonyl-4-[4-(2-oxazolin-2-yl)benzylidene]piperidine, dissolved in 70 ml of anhydrous ethanol and 20 ml of ethyl acetate, are catalytically hydrogenated (ambient temperature, 20 minutes, hydrogen pressure 50 psi) in the presence of 2.5 g of palladium-carbon (10%). The catalyst is suction-filtered, the filtrate is evaporated down and the residue is reacted further without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05466687 |
| Source dataset | uspto-grants-1995_11 |
| ORD ID | ord-57e22a9df6d9489cbc5b5db2a5f43a60 |
| Source note | uspto-grants-1995_11 |