HCID 15289120, compound → HCID 15289121, compound

HRID 1290857Notes

Reaction equation

HRID 1290857 reaction equation
[CH2:1]([N:8]1[C:16](=O)[CH:15]2[CH:10]([C:11]3([C:20]#[N:21])[CH2:19][CH2:18][CH:14]2[CH:13]=[CH:12]3)[C:9]1=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[NH2:21][CH2:20][C:11]12[CH2:19][CH2:18][CH:14]([CH:13]=[CH:12]1)[CH:15]1[CH:10]2[CH2:9][N:8]([CH2:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[CH2:16]1

Participants

3

Reactant 2

HCID 15289120HCID 15289120, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 15289121HCID 15289121, compound

Procedure

14.6 g (50 mmol) of 4benzyl-1-cyano-4-azatricyclo[5.2.2.02,6 ]undec-8-ene-3,5-dione are reduced with 5 g of LiAlH4 as described under Z 1-B and the mixture is worked up accordingly.

Sources & evidence

ORD record
ord-73445df9c32d45be95ba51a3dfc8ed75
Source dataset
uspto-grants-1998_05
Patent number
US05753669

Reaction notes

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