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Thionyl Chloride → 1-Isopropyl-2-oxo-1,2-dihydro-3-quinolinecarbonyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 1-Isopropyl-2-oxo-1,2-dihydro-3-quinolinecarboxylic acid | HCID 10944290 | — |
| 溶媒 | Toluene | HCID 1140 | — |
| 生成物 | 1-Isopropyl-2-oxo-1,2-dihydro-3-quinolinecarbonyl chloride | HCID 15468683 | — |
反応手順
A solution of 3.88 g of 1-isopropyl-2-oxo-1,2-dihydro-3-quinolinecarboxylic acid and 5.0 ml of thionyl chloride in 50 ml of toluene was stirred at 100° C. for 5 hours. After toluene was distilled off under vacuum, toluene was again added to the residue. The solvent was again distilled off under vacuum to give 4.22 g of 1-isopropyl-2-oxo-1,2-dihydro-3-quinolinecarbonyl chloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05753673 |
| 出典データセット | uspto-grants-1998_05 |
| ORD ID | ord-bf647cf64f954d1f9bfdaef159ac3392 |
| 出典メモ | uspto-grants-1998_05 |