2-((Propan-2-yl)amino)benzaldehyde → 2-Isopropylaminobenzaldehyde hydrochloride

HRID 1290892Notes

Reaction equation

HRID 1290892 reaction equation
[CH:1]([NH:4][C:5]1[CH:12]=[CH:11][CH:10]=[CH:9][C:6]=1[CH:7]=[O:8])([CH3:3])[CH3:2].C(OC(=O)C)C.[ClH:19]>C1(C)C=CC=CC=1>[ClH:19].[CH:1]([NH:4][C:5]1[CH:12]=[CH:11][CH:10]=[CH:9][C:6]=1[CH:7]=[O:8])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 110410352-((Propan-2-yl)amino)benzaldehydeHCID 21866389Hydrogen chloride-ethyl acetate

Product 1

HCID 189196242-Isopropylaminobenzaldehyde hydrochloride

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

The thus obtained 2-isopropylaminobenzaldehyde was dissolved in toluene and 4N hydrochloric acid ethyl acetate solution was added thereto under ice cooling. Thus, 42.6 g of 2-isopropylaminobenzaldehyde hydrochloride was obtained.

Sources & evidence

ORD record
ord-d46cc5eb29f54c77968922eb2b626559
Source dataset
uspto-grants-1998_05
Patent number
US05753673

Reaction notes

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