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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1290911Generated: October 30, 2026

4H-Furo[2,3-e]pyrrolo[1,2-a][1,4]diazepine → 9,10-Dihydro-4H-furo[2,3-e]pyrrolo[1,2-a][1,4]diazepine

https://huagongshe.com/reaction/1290911

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4H-Furo[2,3-e]pyrrolo[1,2-a][1,4]diazepineHCID 11819471—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product9,10-Dihydro-4H-furo[2,3-e]pyrrolo[1,2-a][1,4]diazepineHCID 21836966—

Reaction Steps

A solution of 1 mmol of 4H-furo[2,3-e]pyrrolo[1,2-a][1,4]diazepine and 0.2 g of 10% Pd/C in 10 ml of ethanol is hydrogenated for 18 hours. The reaction mixture is filtered through diatomaceous earth and the filtrate is evaporated in vacuo to give the desired product as a solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05753648
Source datasetuspto-grants-1998_05
ORD IDord-2562d86248e1453f84117e06f7232095
Source noteuspto-grants-1998_05