Acetic Acid → 4-[[2-(Phenylmethyl)benzoyl]amino]benzoic Acid

HRID 1290937Notes

Reaction equation

HRID 1290937 reaction equation
[C:1]1([CH2:7][C:8]2[CH:25]=[CH:24][CH:23]=[CH:22][C:9]=2[C:10]([NH:12][C:13]2[CH:21]=[CH:20][C:16]([C:17]([O-:19])=[O:18])=[CH:15][CH:14]=2)=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Na+].C(O)(=O)C>O>[C:1]1([CH2:7][C:8]2[CH:25]=[CH:24][CH:23]=[CH:22][C:9]=2[C:10]([NH:12][C:13]2[CH:14]=[CH:15][C:16]([C:17]([OH:19])=[O:18])=[CH:20][CH:21]=2)=[O:11])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 23698996HCID 23698996, compound

Product 1

HCID 220996974-[[2-(Phenylmethyl)benzoyl]amino]benzoic AcidYield 100%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 4.0 g sodium 4-[[2-(phenylmethyl)benzoyl]amino]benzoate is suspended in water and the pH adjusted to 5 with acetic acid. The solid is collected by filtration and dried at 80° C. in vacuo to give 3.75 g of the desired product, 246°-247° C. M+ =332.

Workup

  1. filtrationThe solid is collected by filtration
  2. customdried at 80° C. in vacuo

Sources & evidence

ORD record
ord-6471f80e2666429ba2baccaaed23a85b
Source dataset
uspto-grants-1998_05
Patent number
US05753648

Reaction notes

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