HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4'-(Trifluoromethyl)(1,1'-biphenyl)-2-carboxylic acid | HCID 55251 | — |
| Product | 4'-(Trifluoromethyl)-[1,1'-biphenyl]-2-carbonyl chloride | HCID 11066000 | — |
Reaction Steps
A mixture of 5.0 g of 4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxylic acid in 5.0 ml of thionyl chloride is heated on a steam bath under Argon for 1 hour and hexane added. The resulting solid is collected and dried to give 5.36 g of the desired product as a colorless oil. M+ =280 as methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05753648 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-81b3b0dd9bee4f2eb109a3093fefcd15 |
| Source note | uspto-grants-1998_05 |