Sodium Hydroxide → HCID 67671474, compound

HRID 1290996Notes

Reaction equation

HRID 1290996 reaction equation
[ClH:1].[C:2]([C:5]1[CH:18]=[CH:17][C:8]2[CH:9]=[C:10]([C:12]([O:14]CC)=[O:13])[O:11][C:7]=2[CH:6]=1)(=[NH:4])[NH2:3].[OH-].[Na+]>>[ClH:1].[C:2]([C:5]1[CH:18]=[CH:17][C:8]2[CH:9]=[C:10]([C:12]([OH:14])=[O:13])[O:11][C:7]=2[CH:6]=1)(=[NH:3])[NH2:4]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 18919452HCID 18919452, compound

Product 1

HCID 67671474HCID 67671474, compoundYield 56.3%

Procedure

Ethyl 6-amidino-2-benzofurancarboxylate hydrochloride (129 mg, 0.480 mmol) was hydrolyzed with a 1N aqueous sodium hydroxide solution to give 65 mg of 6-amidino-2-benzofurancarboxylic acid hydrochloride as a brown solid (56%).

Sources & evidence

ORD record
ord-ef8f52b63e6e437bbf7dd6e9e7f135ee
Source dataset
uspto-grants-1998_05
Patent number
US05753670

Reaction notes

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