HuagongsheHuagongshe Chemistry Print Report · For research reference only
t-Butyl 4-[(6-cyano-1-methyl-2-indolyl)carbonylamino]phenoxyacetate → t-Butyl 4-[(6-amidino-1-methyl-2-indolyl)carbonylamino]phenoxyacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | t-Butyl 4-[(6-cyano-1-methyl-2-indolyl)carbonylamino]phenoxyacetate | HCID 10763801 | — |
| Reactant | 6-cyano-1-methyl-1H-indole-2-carboxylic acid | HCID 10798077 | — |
| Reactant | Tert-butyl 2-(4-aminophenoxy)acetate | HCID 22060435 | — |
| Product | t-Butyl 4-[(6-amidino-1-methyl-2-indolyl)carbonylamino]phenoxyacetate | HCID 10598318 | — |
Reaction Steps
In the same manner as in Example 1 (2), 6-cyano-1-methyl-2-indolcarboxylic acid (52 mg, 0.26 mmol) and t-butyl 4-aminophenoxyacetate (63 mg, 0.29 mmol) were condensed to quantitatively give 109 mg of t-butyl 4-[(6-cyano-1-methyl-2-indolyl)carbonylamino]phenoxyacetate as a colorless solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05753670 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-67e2bbf8f4814ee4a3e4fcb7022d2193 |
| Source note | uspto-grants-1998_05 |