HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-(2-Methylimidazol-1-yl)benzyl chloride hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | [4-(2-Methylimidazol-1-yl)phenyl]methanol | HCID 11735617 | — |
| Product | 4-(2-Methylimidazol-1-yl)benzyl chloride hydrochloride | HCID 18786342 | — |
Reaction Steps
4-(2-Methylimidazol-1-yl)benzyl alcohol (1.28 g, 6.8 mmol) in SOCl2 (5 ml) was stirred at ambient temperature for 30 minutes and then volatiles removed under reduced pressure. The resultant crude product was washed with minimal dry Et2O and dried in vacuo to afford 4-(2-methylimidazol-1-yl)benzyl chloride hydrochloride (1.65 g, quant.) as white solids.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05753682 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-764df86e33d54e3e9a39ec0d771df97e |
| Source note | uspto-grants-1998_05 |