2-Methylimidazole → 3-Fluoro(2-methylimidazol-1-yl)benzyl alcohol

HRID 1291059Notes

Reaction equation

[CH3:1][C:2]1[NH:3][CH:4]=[CH:5][N:6]=1.[F:7][C:8]1[CH:9]=[C:10]([CH:16]=[CH:17][C:18]=1F)[C:11](OCC)=[O:12]>>[F:7][C:8]1[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=1)[CH:11]([OH:12])[N:3]1[CH:4]=[CH:5][N:6]=[C:2]1[CH3:1]

Participants

Reactant 2

HCID 127492-Methylimidazole

HCID 2737171Ethyl 3,4-difluorobenzoate

Product 1

HCID 540353593-Fluoro(2-methylimidazol-1-yl)benzyl alcohol

Procedure

Prepared from 2-methylimidazole and ethyl 3,4-difluorobenzoate.

Sources & evidence

ORD record: ord-b89be0b264c641ff86aaf6333a2a53d7
Source dataset: uspto-grants-1998_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05753682

Reaction notes

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