Benzoyl chloride → HCID 15124790, compound

Participants

Reaction Steps

0.5 g (0.00216 mol) of 1-benzyl-4-hydroxypiperidine and 0.64 ml (0.0046 mol) of triethylamine were dissolved in 20 ml of toluene, treated with 0.313 ml (0.0027 mol) of benzoyl chloride and boiled at reflux for 6 hrs. The suspension was filtered, the filtrate was concentrated and the residue was chromatographed over silica gel with ethyl acetate/hexane (1:3) as the eluent. 0.525 g (82%) of 1-benzyl-piperidin-4-yl benzoate was obtained as yellowish oil.

Provenance & Evidence