Sulfuric Acid → HCID 178481660, compound

HRID 1291202Notes

Reaction equation

HRID 1291202 reaction equation
S(=O)(=O)(O)O.C([O:8][C:9]([CH:11]1[CH2:15][CH2:14][CH2:13][C:12]1=O)=O)C.[CH3:17][NH:18][C:19]([NH2:21])=[S:20]>>[SH:20][C:19]1[N:18]([CH3:17])[C:9](=[O:8])[C:11]2[CH2:15][CH2:14][CH2:13][C:12]=2[N:21]=1

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 69136Ethyl 2-oxocyclopentanecarboxylateHCID 2723704Methylthiourea

Product 1

HCID 178481660HCID 178481660, compoundYield 28%

Conditions

Temperature
100 °C

Procedure

Five (5) drops of concentrated sulfuric acid were added to a mixture of 2-ethoxycarbonylcyclopentanone (31.2 g) and methylthiourea (18.0 g) and the mixture was heated at 100° C. for 2 days. The resulting precipitate was collected by filtration, rinsed with ethanol, and dried to provide the title compound as colorless powder (10.2 g).

Workup

  1. filtrationThe resulting precipitate was collected by filtration
  2. washrinsed with ethanol
  3. customdried

Sources & evidence

ORD record
ord-15345600f0db4791a4695216de298b14
Source dataset
uspto-grants-1998_05
Patent number
US05753664

Reaction notes

Loading…