Hydrazine → HCID 178434371, compound

HRID 1291230Notes

Reaction equation

HRID 1291230 reaction equation
[C:1]([C:4]1[C:5](=[O:14])[N:6]([CH3:13])[N:7]=[CH:8][C:9]=1[N:10](C)C)(=O)[CH3:2].[NH2:15]N>C(O)C>[CH3:2][C:1]1[C:4]2[C:5](=[O:14])[N:6]([CH3:13])[N:7]=[CH:8][C:9]=2[NH:10][N:15]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 18918911HCID 18918911, compound

Product 1

HCID 178434371HCID 178434371, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4-Acetyl-5-dimethylamino-2-methyl-3(2H)-pyridazinone (137 mg) was added to hydrazine (224 mg)/ethanol (5 ml) and the mixture was refluxed with stirring for 6 hours. After the ethanol-hydrazine was distilled off, the residue was washed with diethyl ether and dried. White powder, 114 g. 1H-NMR (CDCl3) 8: 2.57(3H,s), 3.64(3H,s), 8.30(1H,s).

Workup

  1. temperaturethe mixture was refluxed
  2. distillationAfter the ethanol-hydrazine was distilled off
  3. washthe residue was washed with diethyl ether
  4. customdried

Sources & evidence

ORD record
ord-780ebb2529f14e6dbc87b95d17a7162c
Source dataset
uspto-grants-1998_05
Patent number
US05753664

Reaction notes

Loading…