反应详情

4-Acetyl-5-dimethylamino-2-methyl-3(2H)-pyridazinone (137 mg) was added to hydrazine (224 mg)/ethanol (5 ml) and the mixture was refluxed with stirring for 6 hours. After the ethanol-hydrazine was distilled off, the residue was washed with diethyl ether and dried. White powder, 114 g. 1H-NMR (CDCl3) 8: 2.57(3H,s), 3.64(3H,s), 8.30(1H,s).

1. temperaturethe mixture was refluxed
2. distillationAfter the ethanol-hydrazine was distilled off
3. washthe residue was washed with diethyl ether
4. customdried