HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanol → HCID 54309039, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanol | HCID 10631861 | — |
| Reactant | HCID 15285749 | HCID 15285749 | — |
| Reactant | 1,3-Dihydro-1-[4-(1-methylethyl)phenyl]-2H-imidazol-2-one | HCID 19373696 | — |
| Product | HCID 54309039 | HCID 54309039 | 13.9% |
Reaction Steps
In the same manner as in Reference Example 5, starting from 0.83 g of (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl]ethanol and 0.83 g of 1-(4-isopropylphenyl)-2(1H,3H)-imidazolone, 1-[(1R,2S)-2-(2,4-difluorophenyl)-2,3-epoxy-1-methylpropyl]-3-(4-isopropylphenyl)-2(1H,3H)-imidazolone (0.25 g) and 0.22 g of (2R)-2-(2,4-difluorophenyl)-2-[(1R)-1-[1-(4-isopropylphenyl)-2-imidazolyloxy]ethyl] oxiran were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05466820 |
| Source dataset | uspto-grants-1995_11 |
| ORD ID | ord-3358990dcb714690ab485037cf7616a7 |
| Source note | uspto-grants-1995_11 |