Potassium Carbonate → HCID 18918910, compound

Participants

Reaction Steps

A solution of 2-[4-(4-hydroxybenzoyl)benzylthio]-3,5-dimethyl-4(3H)-quinazolinone (369 mg), 4-picolyl chloride hydrochloride (144 mg) and potassium carbonate (350 mg) in DMF (5 ml) was stirred at room temperature for 3 days. This reaction mixture was concentrated and the residue was dissolved in ethyl acetate, washed with water, dried, and concentrated. The residue was recrystallized from ethyl acetate-chloroform to provide the title compound as colorless solid (99 mg).

Provenance & Evidence