(1S)-[(2R)-(2,4-difluorophenyl)-2-oxiranyl]ethanol → HCID 18657633, compound

Participants

Reaction Steps

In the same menner as in Reference Example 5, starting from 1.38 g of (1S)-1-[(2R)-2-(2,4-difluorophenyl)-2-oxiranyl]ethanol and 1.21 g of 4-(3-methylbutyl)-3(2H,4H)-1,2,4-triazolone, 2-[(1R, 2S)-2-(2,4-Difluorophenyl)-2,3-epoxy-1-methylpropyl]-4-(3-methylbutyl)-3 (2H, 4H)-1,2,4-triazolone (1.15 g) was obtained as a colorless oil.

Provenance & Evidence