HCID 69961015, compound → HCID 18918955, compound

Participants

Reaction Steps

To a solution of 2-[2-[4-(4-chlorobenzoyl)phenyl]-vinyl]-3,5-dimethyl-4(3H)-quinazolinone (104 mg) in THF-ethyl acetate-methanol (2:1:1) (20 ml) was added 10% Pd/C (50% hydrous) (10 mg) and the mixture was stirred under hydrogen at room temperature for 2 hours. The catalyst was then filtered off and the filtrate was concentrated. The residue was washed with ethyl acetate-methanol and dried to provide 53 mg of white powder.

Provenance & Evidence