Hydrochloric Acid → HCID 69962553, compound

Participants

Reaction Steps

3-Acetoxyethyl-7-[4-(4-chlorobenzoyl)benzyl]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-one (464 mg) was dissolved in methanol (12 ml) followed by addition of 1N-sodium hydroxide (2 ml). To this mixture was added DME (6 ml) to prepare a homogeneous solution. After 4 hours of stirring, 1N-HCl (2 ml) was added and the solvent was distilled off under reduced pressure. The residue was diluted with water and triturated and the resulting powder was rinsed with water and methanol and dried to provide the title compound as crystalline powder (402 mg).

Provenance & Evidence