Methyl iodide → 131988-12-0

HRID 1291436Notes

Reaction equation

HRID 1291436 reaction equation
[CH3:1][I:2].[CH2:3]([O:5][C:6]1[C:10]([C:11]2[CH:12]=[N:13][CH:14]=[CH:15][CH:16]=2)=[N:9][S:8][N:7]=1)[CH3:4]>CC(C)=O>[I-:2].[CH2:3]([O:5][C:6]1[C:10]([C:11]2[CH:12]=[N+:13]([CH3:1])[CH:14]=[CH:15][CH:16]=2)=[N:9][S:8][N:7]=1)[CH3:4]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 15180131Pyridine, 3-(4-ethoxy-1,2,5-thiadiazol-3-yl)- (9CI)

Product 1

HCID 15819042131988-12-0

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.3 ml, 5 mmol) and 3-(3-ethoxy-1,2,5-thiadiazol-4-yl) pyridine (520 mg, 2.5 mmol) in acetone (10 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.72 g (83%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.72 g (83%)

Sources & evidence

ORD record
ord-db1908e9f7ab4d9283c9c3fbdce12260
Source dataset
uspto-grants-1998_05
Patent number
US05753683

Reaction notes

Loading…