Methyl iodide → HCID 19075352, compound

HRID 1291452Notes

Reaction equation

HRID 1291452 reaction equation
[CH3:1][I:2].[CH2:3]([O:7][C:8]1[C:12]([C:13]2[CH:14]=[N:15][CH:16]=[CH:17][CH:18]=2)=[N:11][S:10][N:9]=1)[C:4]#[C:5][CH3:6]>CC(C)=O>[I-:2].[CH2:3]([O:7][C:8]1[C:12]([C:13]2[CH:14]=[N+:15]([CH3:1])[CH:16]=[CH:17][CH:18]=2)=[N:11][S:10][N:9]=1)[C:4]#[C:5][CH3:6]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 19075318HCID 19075318, compound

Product 1

HCID 19075352HCID 19075352, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl iodide (0.5 ml, 7.5 mmol) and 3-(3-(2-butynyloxy)-1,2,5-thiadiazol-4-yl)pyridine (578 mg, 2.5 mmol) in acetone (5 ml) was stirred at room temperature for 18 h. The title compound precipitated from the solution and was collected by filtration to yield 0.88 g (95%).

Workup

  1. customThe title compound precipitated from the solution
  2. filtrationwas collected by filtration
  3. customto yield 0.88 g (95%)

Sources & evidence

ORD record
ord-8ab1b3b99d5c4cc3983cbc5b3d1dcf4c
Source dataset
uspto-grants-1998_05
Patent number
US05753683

Reaction notes

Loading…