1-Bromo-4-pentyne → HCID 19612611, compound

HRID 1291535Notes

Reaction equation

HRID 1291535 reaction equation
[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[CH2:7]([S:12][C:13]1[C:17]([C:18]2[CH2:19][N:20]([CH3:24])[CH2:21][CH2:22][CH:23]=2)=[N:16][O:15][N:14]=1)[CH2:8]CC#C.Cl[C:26]1[C:30]([C:31]2C=N[CH:34]=[CH:35][CH:36]=2)=NON=1.S.[Na].BrCCCC#C>>[C:1]([OH:6])(=[O:5])[C:2]([OH:4])=[O:3].[O:3]([CH2:8][CH2:7][S:12][C:13]1[C:17]([C:18]2[CH2:19][N:20]([CH3:24])[CH2:21][CH2:22][CH:23]=2)=[N:16][O:15][N:14]=1)[C:26]1[CH:30]=[CH:31][CH:36]=[CH:35][CH:34]=1

Participants

5

Reactant 4

HCID 121175751-Bromo-4-pentyneHCID 15180172HCID 15180172, compoundHCID 19075447HCID 19075447, compoundHCID 86586439Sodium hydrogen sulphide

Product 1

HCID 19612611HCID 19612611, compound

Procedure

3-(3-(4-Pentynylthio)-1,2,5-oxadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine oxalate from 3-(3-chloro-1,2,5-oxadiazol-4-yl)pyridine, sodium hydrogensulfide and 1-bromo-4-pentyne. M.p. 119°-120° C. Compound 214.

Sources & evidence

ORD record
ord-bddc36a60dce409c9bb0a148189f5424
Source dataset
uspto-grants-1998_05
Patent number
US05753683

Reaction notes

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