Potassium Hydroxide → 5-(3-Buten-1-ynyl)-2,2'-bithiophene

HRID 1291601Notes

Reaction equation

HRID 1291601 reaction equation
Cl[CH2:2][CH2:3][C:4]#[C:5][C:6]1[S:10][C:9]([C:11]2[S:12][CH:13]=[CH:14][CH:15]=2)=[CH:8][CH:7]=1.[OH-].[K+]>C(O)C>[C:5]([C:6]1[S:10][C:9]([C:11]2[S:12][CH:13]=[CH:14][CH:15]=2)=[CH:8][CH:7]=1)#[C:4][CH:3]=[CH2:2]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 18920422HCID 18920422, compound

Product 1

HCID 708135-(3-Buten-1-ynyl)-2,2'-bithiophene

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Conditions

Temperature
75 °C

Procedure

5-(4-chloro-1-butynyl)-2,2'-bithiophene was dissolved in ethanol. KOH dissolved in ethanol was then added in and heated at 75° C. for 15 minutes. The remaining process was as described in procedure(a) and the same product was obtained. The yield was above 90%.

Workup

  1. additionwas then added in and
  2. customthe same product was obtained

Sources & evidence

ORD record
ord-98216600e7024947a1dfbc91fcf577f8
Source dataset
uspto-grants-1998_05
Patent number
US05753692

Reaction notes

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