HCID 53695966, compound → HCID 18918255, compound

Participants

Reaction Steps

To a solution of the product of step (iii) (3.6 g) in absolute ethanol (100 ml) was added 5% palladium/charcoal catalyst, and the mixture hydrogenated at ambient temperature and pressure until the theoretical volume of hydrogen had been consumed. The catalyst was removed by filtration through celite and the filtrate evaporated to yield ethyl 2-(4-dimethylamino-3-pyridyl)propanoate as a pale yellow oil (3.1 g) NMR (d6DMSO) : δ 1.15 (3H,t); 2.65 (2H,t); 2.8 (6H,s); 2.9 (2H,t); 4.05 (2H,q); 6.8 (2H,d); 8.2 (2H,d); m/e 223 (M+H)+.

Provenance & Evidence