反应详情

Preparation of 3,5-difluoro-4-cyanophenyl 4-(pentyloxymethyl)benzoate (in the formula (1), R=C5H11, l=1, m=1, n and o=both, 0; A1 =1,4- phenylene group, Z1 =--COO--, X=CN, and Y1 and Y2 =both, F) (Compound No. 1)) 4-(Pentyloxymethyl)benzoic acid. (1.6 g, 7.1 mmol) was mixed with thionyl chloride (1.3 g, 10.6 mmol), pyridine (0.1 ml) and toluene (3 ml), followed by reacting them at 80° C. for 2 hours, and distilling off superfluous thionyl chloride and toluene under reduced pressure, to obtain raw 4-(pentyloxymethyl)benzoyl chloride.

1. customat 80° C.
2. customfor 2 hours
3. distillationdistilling off superfluous thionyl chloride and toluene under reduced pressure