反应详情

0.56 g (3 mmol) 3-Chloro-2-hydrazino-4,5,6,7-tetrahydro-pyrazolo[1,5-a]pyridine was dissolved in 5 ml ethanol and treated with 0.42 g (3 mmol) 2-ethoxymethylen-3-oxobutyro-nitrile. After heating under reflux for 3 hours, the mixture was concentrated and the residue purified by silica gel chromatography (hexane/ethyl acetate 1:1).

1. temperatureAfter heating
2. temperatureunder reflux for 3 hours
3. concentrationthe mixture was concentrated
4. customthe residue purified by silica gel chromatography (hexane/ethyl acetate 1:1)