HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Ethoxymethylene)propanedinitrile → 5-Amino-4-cyano-1-(1-methyl-5-methylmercapto-3-pyrazolyl)pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Ethoxymethylene)propanedinitrile | HCID 67152 | — |
| Reactant | 3-Hydrazino-1-methyl-5-methylmercaptopyrazole | HCID 45121314 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-Amino-4-cyano-1-(1-methyl-5-methylmercapto-3-pyrazolyl)pyrazole | HCID 54178897 | — |
Reaction Steps
A mixture of 2.0 g (13.1 mmol) 3-Hydrazino-1-methyl-5-methylmercaptopyrazole and 1.8 g (14.4 mmol) ethoxymethylenemalononitrile in 25 ml ethanol was stirred for 30 minutes at room temperature and heated at boiling point for 3 hours. The reaction mixture was concentrated and the residue purified by silica gel chromatography (hexane/ethyl acetate 1:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05756424 |
| Source dataset | uspto-grants-1998_05 |
| ORD ID | ord-f358d2c2f8c9402d9d886f0ddbfebc6d |
| Source note | uspto-grants-1998_05 |