Methylhydrazine → 3-Amino-1-methyl-5-methylsulfanyl-1H-pyrazole-4-carbonitrile

HRID 1292014Notes

Reaction equation

HRID 1292014 reaction equation
CS[C:3](=[C:6]([C:9]#[N:10])[C:7]#[N:8])[S:4][CH3:5].[CH3:11][NH:12][NH2:13]>O>[NH2:8][C:7]1[C:6]([C:9]#[N:10])=[C:3]([S:4][CH3:5])[N:12]([CH3:11])[N:13]=1

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 992292-(Bis(methylsulfanyl)methylidene)propanedinitrile

Product 1

HCID 28195393-Amino-1-methyl-5-methylsulfanyl-1H-pyrazole-4-carbonitrile

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

9.63 g (56.6 mmol) [Bis(methylmercapto)methylene]-malononitrile was suspended in 50 ml water and treated with 3.7 ml (67.9 mmol) methylhydrazine. The mixture was heated at boiling for 1 hour, the reaction solution cooled, the precipitate suction filtered and recrystallised from ethanol.

Workup

  1. temperatureThe mixture was heated
  2. temperaturethe reaction solution cooled
  3. filtrationthe precipitate suction filtered
  4. customrecrystallised from ethanol

Sources & evidence

ORD record
ord-64d4361da438417cbb63673d868528dd
Source dataset
uspto-grants-1998_05
Patent number
US05756424

Reaction notes

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