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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1292072Generated: October 30, 2026

4-(3-Azabicyclo[3.2.2]non-3-yl)butylamine → N-[4-(3-Azabicyclo[3.2.2]non-3-yl)butyl]-6,7,8,9-tetrahydro-4-methylpyridazino[4,5-b]indolizin-1-amine

https://huagongshe.com/reaction/1292072

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Azabicyclo[3.2.2]non-3-yl)butylamineHCID 13511081—
Reactant1-Chloro-4-methyl-6,7,8,9-tetrahydropyridazino[4,5-b]indolizineHCID 86752616—
ProductN-[4-(3-Azabicyclo[3.2.2]non-3-yl)butyl]-6,7,8,9-tetrahydro-4-methylpyridazino[4,5-b]indolizin-1-amineHCID 9842921—

Reaction Steps

Following the procedure in Example 9, compound XII was allowed to react with 4-(3-azabicyclo[3.2.2]non-3-yl)butylamine to give the title compound which was converted to the dihydrochloride salt: m.p.210° C. (dec.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05756501
Source datasetuspto-grants-1998_05
ORD IDord-bee5ec45d8a545a4b5f557a978972860
Source noteuspto-grants-1998_05