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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1292239Generated: October 28, 2026

HCID 22860484, compound → Propanoic acid, 2-methyl-3-(methylsulfonyl)-, (S)-

https://huagongshe.com/reaction/1292239

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22860484HCID 22860484—
Solvent1,4-Dioxane hydrochlorideHCID 20443148—
ProductPropanoic acid, 2-methyl-3-(methylsulfonyl)-, (S)-HCID 1581419171.9%

Reaction Steps

To 2.68 g of 2(S)-methyl-3-(methylsulfonyl)propionic acid t-butyl ester was added 20 mL of 4N hydrochloric acid/dioxane and the mixture stirred at room temperature for 19 hours. The solvent was removed in vacuo to afford 2.18 g of crude product, which was recrystallized from ethyl acetate/hexane to yield 1.44 g of 2(S)-methyl-3-(methylsulfonyl)-propionic acid as white crystals: ##STR76##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05756534
Source datasetuspto-grants-1998_05
ORD IDord-b2d6c3585f014e7590b75fe3488156f7
Source noteuspto-grants-1998_05