化工社化工社 化学情報印刷レポート · 研究参考用
Acetic Acid → N-Acetyl-L-proline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Trifluoroacetic acid | HCID 6422 | — |
| 反応物 | Acetic Anhydride | HCID 7918 | — |
| 反応物 | Ammonium thiocyanate | HCID 15666 | — |
| 溶媒 | Triethylamine | HCID 8471 | — |
| 生成物 | N-Acetyl-L-proline | HCID 66141 | — |
反応手順
ammonium thiocyanate (BDH, Analar), Aristar acetic acid (BDH), eptide synthesis grades of trifluoroacetic acid and acetic anhydride (Applied Biosystems) were used without further purification. Reagents for amino acid analysis of phenylthiocarbamyl amino acids were all of the highest possible purity (Inglis et al Biochem. Biophys. Methods 15:249, 1988). Pierce 6M constant boiling HC1 and Analar phenol (BDH) were used for hydrolysis and N,N-diisopropylethylamine (DIEA, Peptide Synthesis Grade, Applied Biosystems) replaced triethylamine in the drying reagent and in the coupling buffer.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05756667 |
| 出典データセット | uspto-grants-1998_05 |
| ORD ID | ord-34e412f94b714d90839c31b45566e546 |
| 出典メモ | uspto-grants-1998_05 |