Methyl iodide → HCID 18914255, compound

HRID 1292411Notes

Reaction equation

HRID 1292411 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]([C:9]2[NH:10][C:11]3[C:16]([C:17]=2[CH2:18][N:19]([CH3:21])[CH3:20])=[CH:15][CH:14]=[CH:13][CH:12]=3)[CH:5]=[C:6]([CH3:8])[CH:7]=1.[I:22][CH3:23]>>[I-:22].[CH3:1][C:2]1[CH:3]=[C:4]([C:9]2[NH:10][C:11]3[C:16]([C:17]=2[CH2:18][N+:19]([CH3:23])([CH3:21])[CH3:20])=[CH:15][CH:14]=[CH:13][CH:12]=3)[CH:5]=[C:6]([CH3:8])[CH:7]=1

Participants

3

Reactant 2

HCID 6328Methyl iodideHCID 18914246HCID 18914246, compound

Product 1

HCID 18914255HCID 18914255, compound

Procedure

To a solution of [2-(3,5-dimethylphenyl)-1H-indol-3-ylmethyl]dimethylamine (350 mg in 4 mL diethyl ether) was added 0.5 mL iodomethane and the mixture stirred at room temperature. After 3 hours, the mixture was filtered and the solids dried in vacuo to provide the crude title compound. (414 mg).

Workup

  1. filtrationthe mixture was filtered
  2. customthe solids dried in vacuo

Sources & evidence

ORD record
ord-66a984a9adb34aa2b57b12bbd1fc1b45
Source dataset
uspto-grants-1998_05
Patent number
US05756507

Reaction notes

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