Ammonia → HCID 18915530, compound

Participants

Reaction Steps

An aqueous 28% ammonia solution (12.1 g, 200 mmol) and o-chlorobenzaldehyde (3.65 g, 26 mmol) were mixed and a solution prepared by dissolving propargyl methanesulfonate (2.68 g, 20 mmol) in 10.7 g of toluene was added dropwise at 20° C. over 0.6 hour to the solution, followed by stirring at the same temperature for 10 hours. After separating, the resulting organic phase was concentrated to obtain a crude product of N-(2-chlorobenzylidene)-2-propynylamine.

Provenance & Evidence