Water → HCID 178527028, compound

HRID 1292624Notes

Reaction equation

HRID 1292624 reaction equation
[CH:1]1([P:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[O:8]CC)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.O>>[CH:11]1([PH:7](=[O:8])[C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 962WaterHCID 18915967HCID 18915967, compound

Product 1

HCID 178527028HCID 178527028, compoundYield 96%

Procedure

36 g (0.153 mol) of ethyl cyclohexylphenylphosphinite are heated to 90° C. under a nitrogen atmosphere and 2.9 g (0.161 mol) of water are added dropwise with constant stirring in the course of 3 hours. The batch is further stirred at 85° to 90° C. for 3 hours. An ethanol/water mixture is then distilled off in vacuo up to an internal temperature of 95° C. 30.5 g of cyclohexylphenylphosphine oxide are obtained as residue. This corresponds to a yield of 96% of theory.

Workup

  1. stirringThe batch is further stirred at 85° to 90° C. for 3 hours
  2. distillationAn ethanol/water mixture is then distilled off in vacuo up to an internal temperature of 95° C

Sources & evidence

ORD record
ord-fb4bb6c7e4534182bb61e9632840578c
Source dataset
uspto-grants-1998_05
Patent number
US05756848

Reaction notes

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