6-Heptynoic acid → 1-(Pent-4-ynyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2.2.2]octane

HRID 129267Notes

Reaction equation

HRID 129267 reaction equation
C(O)(=O)CCCCC#C.OC(C1(CCC)COC1)C(F)(F)F.[CH2:23]([C:29]12[O:36][CH2:35][C:32]([CH2:37][CH2:38][CH3:39])([CH2:33][O:34]1)[CH:31]([C:40]([F:43])([F:42])[F:41])[O:30]2)[CH2:24][CH2:25][CH2:26][C:27]#C>>[CH2:23]([C:29]12[O:36][CH2:35][C:32]([CH2:37][CH2:38][CH3:39])([CH2:33][O:34]1)[CH:31]([C:40]([F:41])([F:42])[F:43])[O:30]2)[CH2:24][CH2:25][C:26]#[CH:27]

Participants

4

Reactant 3

HCID 43779506-Heptynoic acidHCID 150219493-(1-Hydroxy-2,2,2-trifluoroethyl)-3-n-propyloxetaneHCID 193733951-(Hex-5-ynyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2.2.2]octane

Product 1

HCID 193732701-(Pent-4-ynyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2.2.2]octane

Procedure

In an analogous manner the following compound was prepared from hept-6-ynoic acid and 3-(1-hydroxy-2,2,2-trifluoroethyl)-3-n-propyloxetane: 1-(Hex-5-ynyl)-4-propyl-3-trifluoromethyl-2,6,7-trioxabicyclo[2.2.2]octane.

Sources & evidence

ORD record
ord-eff49d0a12214667a7d76fbee3c5cea4
Source dataset
uspto-grants-1995_11
Patent number
US05466710

Reaction notes

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