1-Naphthalenemethanamine → HCID 70341354, compound

HRID 1292689Notes

Reaction equation

HRID 1292689 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:15][C@H:14]([O:16][CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[CH2:13][C@H:9]1[C:10]([OH:12])=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[C:24]1([CH2:34][NH2:35])[C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[CH:27]=[CH:26][CH:25]=1>>[C:24]1([CH2:34][NH:35][C:10](=[O:12])[C@@H:9]2[CH2:13][C@@H:14]([O:16][CH2:17][C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)[CH2:15][N:8]2[C:6]([O:5][C:1]([CH3:3])([CH3:4])[CH3:2])=[O:7])[C:33]2[C:28](=[CH:29][CH:30]=[CH:31][CH:32]=2)[CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 83551-NaphthalenemethanamineHCID 11860409Boc-Hyp(Bzl)-OH

Product 1

HCID 70341354HCID 70341354, compound

Procedure

The title compound was prepared using the procedure in Example 1 step H using N-t-butoxycarbonyl-4(R)-benzyloxyproline and naphth-1-ylmethylamine.

Sources & evidence

ORD record
ord-e56d7e34f60349dca824a657ed9cea68
Source dataset
uspto-grants-1998_05
Patent number
US05756528

Reaction notes

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