Aluminium lithium hydride → HCID 69420884, compound

HRID 1292976Notes

Reaction equation

HRID 1292976 reaction equation
C([O:3][C:4](=O)[C:5]([CH2:17][CH:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1)([OH:16])[CH2:6][C:7]([CH3:15])([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH3:8])C.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH:18]1([CH2:17][C:5]([OH:16])([CH2:6][C:7]([CH3:8])([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH3:15])[CH2:4][OH:3])[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 69422301HCID 69422301, compound

Product 1

HCID 69420884HCID 69420884, compound

Procedure

Analogously to Example 1, 290 mg of 2-cyclohexylmethyl-2-hydroxy-4-methyl-4-phenylpentanoic acid-ethyl ester is converted with 76 mg of lithium aluminum hydride into 160 mg of product.

Sources & evidence

ORD record
ord-66855c2f9f82453da0f9649af757f5b2
Source dataset
uspto-grants-2007_07
Patent number
US07238707B2

Reaction notes

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