HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4S)-4-[2-(4-methoxyphenoxy)ethyl]-2,2-dimethyl-1,3-dioxolane → (2S)-4-(4-methoxyphenoxy)butane-1,2-diol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4S)-4-[2-(4-methoxyphenoxy)ethyl]-2,2-dimethyl-1,3-dioxolane | HCID 67319955 | — |
| Solvent | Acetic acid--water (1/1) | HCID 21899381 | — |
| Product | (2S)-4-(4-methoxyphenoxy)butane-1,2-diol | HCID 67317445 | — |
Reaction Steps
A solution of (4S)-4-[2-(4-methoxyphenoxy)ethyl]-2,2-dimethyl-1,3-dioxolane (8.2 g, 30.8 mmol) in AcOH/water was stirred at rt for 5 h and concentrated in vacuo. The residue was co-evaporated with toluene (3×) and then pumped under high vacuum to give the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07238710B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-f684c40b89e945a7bf4564564e18a292 |
| Source note | uspto-grants-2007_07 |