N-[2-(diisopropylamino)ethyl]-1H-imidazole-1-carboxamide → N-({9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-6-[(9H-fluoren-9-ylmethyl)amino]-9H-purin-2-yl}methyl)-N'-[2-(diisopropylamino)ethyl]urea

Participants

Role	Name	HCID	Charge
Reactant	N-[2-(diisopropylamino)ethyl]-1H-imidazole-1-carboxamide	HCID 21978296	—
Reactant	(2R,3R,4S,5R)-2-{2-(aminomethyl)-6-[(9H-fluoren-9-ylmethyl)amino]-9H-purin-9-yl}-5-(hydroxymethyl)tetrahydro-3,4-furandiol	HCID 60018582	—
Product	N-({9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydro-2-furanyl]-6-[(9H-fluoren-9-ylmethyl)amino]-9H-purin-2-yl}methyl)-N'-[2-(diisopropylamino)ethyl]urea	HCID 60018580	—

Reaction Steps

The title compound was prepared from (2R,3R,4S,5R)-2-{2-(aminomethyl)-6-[(9H-fluoren-9-ylmethyl)amino]-9H-purin-9-yl}-5-(hydroxymethyl)tetrahydro-3,4-furandiol (Preparation 13) and N-[2-(diisopropylamino)ethyl]-1H-imidazole-1-carboxamide (Preparation 27) in a similar procedure to Example 3.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07238676B2
Source dataset	uspto-grants-2007_07
ORD ID	ord-c9e814a30d9449478350a78a54d42a7b
Source note	uspto-grants-2007_07