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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1293056Generated: October 27, 2026

2,2-Bis(3-methylphenyl)ethanamine → HCID 60018586, compound

https://huagongshe.com/reaction/1293056

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Bis(3-methylphenyl)ethanamineHCID 21978312—
Reactant(2R,3R,4R,5R)-4-(Acetyloxy)-2-[(acetyloxy)methyl]-5-(6-chloro-2-cyano-9H-purin-9-yl)tetrahydro-3-furanyl acetateHCID 22948625—
ProductHCID 60018586HCID 60018586—

Reaction Steps

The title compound was prepared from (2R,3R,4R,5R)-4-(acetyloxy)-2-[(acetyloxy)methyl]-5-(6-chloro-2-cyano-9H-purin-9-yl)tetrahydro-3-furanyl acetate (Preparation 45) and 2,2-bis(3-methylphenyl)ethanamine (J. Med. Chem., 1988, 31(7), 1282) using a similar procedure to that of Preparation 64.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07238676B2
Source datasetuspto-grants-2007_07
ORD IDord-4e56778c61f64ec58386e2c6e44a44be
Source noteuspto-grants-2007_07