Thionyl Chloride → HCID 20780078, compound

HRID 1293079Notes

Reaction equation

HRID 1293079 reaction equation
S(Cl)([Cl:3])=O.[CH3:5][C:6]1[N:7]=[C:8]2[N:16]([C:17]3[C:22]([CH3:23])=[CH:21][C:20]([CH3:24])=[CH:19][C:18]=3[CH3:25])[C:15]3[N:14]=[CH:13][CH:12]=[CH:11][C:10]=3[N:9]2[C:26]=1[CH2:27]O>C(Cl)Cl>[Cl:3][CH2:27][C:26]1[N:9]2[C:10]3[CH:11]=[CH:12][CH:13]=[N:14][C:15]=3[N:16]([C:17]3[C:22]([CH3:23])=[CH:21][C:20]([CH3:24])=[CH:19][C:18]=3[CH3:25])[C:8]2=[N:7][C:6]=1[CH3:5]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 20780093HCID 20780093, compound

Product 1

HCID 20780078HCID 20780078, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Thionyl chloride (0.164 mL, 2.25 mmol) was added at 0° C. to a solution of [2-methyl-8-(2,4,6-trimethyl-phenyl)-8H-1,3a,7,8-tetraaza-cyclopenta[α]inden-3-yl]-methanol (0.36 g, 1.12 mmol) in CH2Cl2 (10 mL). After 2 h, solvents was removed and the title compound was obtained as a brownish oil (100% yield). Mass spec.: 335.24 (M−Cl+OMe+H)+.

Workup

  1. customsolvents was removed

Sources & evidence

ORD record
ord-91241a7e03a74b608fdf3936a1529361
Source dataset
uspto-grants-2007_07
Patent number
US07238699B2

Reaction notes

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