Water → 4-Chloro-1-nitro-2-(phenylsulfanyl)benzene

Participants

Reaction Steps

To a solution of 2 g of 2-fluoro-4-chloro-nitrobenzene in 50 ml DMF and 1.25 ml of thiophenol was added 1.9 ml triethylamine at room temperature. The mixture was stirred for one hour. One hundred mL of water was added and a yellow solid crashed out of solution. The solid was collected by filtration and dried. Yield: 50–70%. LC-MS showed a single peak with the expected (M+H+) of 267.

Provenance & Evidence