Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1293170Generated: November 1, 2026

3-Fluorophenol → 5-Fluoro-2-(3-fluorophenoxy)nicotinic acid

https://huagongshe.com/reaction/1293170

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-FluorophenolHCID 9743—
ReactantHCID 178524531HCID 178524531—
Product5-Fluoro-2-(3-fluorophenoxy)nicotinic acidHCID 57572347—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 & 2 of Example 1 from 2-hydroxy-5-fluoronicotinic acid and 3-fluorophenol; 1H-NMR (DMSO-d6) δ 8.37 (1H, m), 8.23–8.15(1H, m), 7.49–7.35 (1H, m), 7.10–6.90 (3H, m).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07238714B2
Source datasetuspto-grants-2007_07
ORD IDord-fe13eb87f0314c38b05c773ec28186bb
Source noteuspto-grants-2007_07