(S)-Methyl 4-(1-aminoethyl)benzoate hydrochloride → HCID 57572327, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 3 of Example 1 from 5-fluoro-2-(3-fluorophenoxy)nicotinic acid (step 1) and methyl 4-[(1S)-1-aminoethyl]benzoate hydrochloride (step 3 of Example 5): 1H-NMR (CDCl3) δ 8.33 (1H, dd, J=8.2, 3.1 Hz), 8.12–7.98 (4H, m), 7.47–7.38 (3H, m), 7.05–6.89 (3H, m), 5.36 (1H, m), 3.90 (3H, s), 1.60 (3H, d, J=6.9 Hz).

Provenance & Evidence