HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2,5-Dichloronicotinate → Methyl 5-chloro-2-(3-methoxybenzyl)nicotinate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2,5-Dichloronicotinate | HCID 2764318 | — |
| Reactant | HCID 178490226 | HCID 178490226 | — |
| Product | Methyl 5-chloro-2-(3-methoxybenzyl)nicotinate | HCID 57572338 | — |
Reaction Steps
The title compound was prepared according to the procedure described in step 2 of Example 58 from methyl 2,5-dichloronicotinate and 3-methoxybenzylzinc chloride: 1H-NMR (CDCl3) δ 8.64 (1H, d, J=2.5 Hz), 8.16 (1H, d, J=2.5 Hz), 7.17 (1H, t, J=7.9 Hz), 6.83–6.70 (3H, m), 4.53 (2H, s), 3.88 (3H, s), 3.75 (3H, s).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07238714B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-3e0a26245f96485bb622b6fa72d6e6c3 |
| Source note | uspto-grants-2007_07 |