反应详情

The title compound was prepared according to the procedure described in step 3 of Example 1 from 5-fluoro-2-(4-fluorophenoxy)benzoic acid (Anales de la Asociacion Quimica Argentina 1985, 73, 509) and methyl 4-(aminomethyl)benzoate hydrochloride: 1H-NMR (CDCl3) δ 7.99 (4H, m), 7.30 (2H, d, J=7.6 Hz), 7.14–7.03 (3H, m), 6.96–6.92 (2H, m), 6.80 (1H, dd, J=9.2, 4.4 Hz), 4.70 (2H, d, J=5.9 Hz), 3.91 (3H, s); MS (ESI) m/z 398 (M+H)+, 396 (M−H)−.