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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1293225Generated: October 30, 2026

3-Fluorophenol → Methyl 5-chloro-2-(3-fluorophenoxy)benzoate

https://huagongshe.com/reaction/1293225

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-FluorophenolHCID 9743—
ReactantMethyl 5-chloro-2-fluorobenzoateHCID 21525433—
ProductMethyl 5-chloro-2-(3-fluorophenoxy)benzoateHCID 57572274—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 67 from methyl 5-chloro-2-fluorobenzoate and 3-fluorophenol: 1H-NMR (CDCl3) δ 7.91 (1H, d, J=2.8 Hz), 7.46 (1H, dd, J=8.7, 2.8 Hz), 7.31–7.06 (1H, m), 6.99 (1H, d, J=8.7 Hz), 6.83–6.61 (3H, m), 3.81 (3H, s).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07238714B2
Source datasetuspto-grants-2007_07
ORD IDord-854c2b0e2a5e4a13b294bce9449398c5
Source noteuspto-grants-2007_07