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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1293237Generated: October 25, 2026

3-Fluorophenol → Methyl 3-bromo-4-(3-fluorophenoxy)benzoate

https://huagongshe.com/reaction/1293237

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-FluorophenolHCID 9743—
ReactantMethyl 3-bromo-4-fluorobenzoateHCID 7018022—
ProductMethyl 3-bromo-4-(3-fluorophenoxy)benzoateHCID 69417169—

Reaction Steps

The title compound was prepared according to the procedure described in step 1 of Example 67 from methyl 3-bromo-4-fluorobenzoate and 3-fluorophenol: 1H-NMR (CDCl3) δ 8.33 (1H, d, J=2.0 Hz), 7.94 (1H, dd, J=8.6, 2.0 Hz), 7.38–7.29 (1H, m), 6.96–6.72 (4H, m), 3.92 (3H, s).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07238714B2
Source datasetuspto-grants-2007_07
ORD IDord-affaf70d925f46ada4753a054696f9a7
Source noteuspto-grants-2007_07