2,4-Dimethylphenol → HCID 69419232, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 45 from methyl 4-((1S)-1-{[(2,5-dichloropyridin-3-yl)carbonyl]amino}ethyl)benzoate (step 1 of Example 48) and 2,4-dimethylphenol: 1H-NMR (CDCl3) δ 8.56 (1H, d, J=2.8 Hz), 8.32 (1H, d, J=7.5 Hz), 8.11 (1H, d, J=2.6 Hz), 8.02–7.98 (2H, m), 7.43 (2H, d, J=8.3 Hz), 7.26–7.09 (2H, m), 6.99 (1H, d, J=8.1 Hz), 5.45–5.36 (1H, m), 3.90 (3H, s), 2.36 (3H, s), 2.10 (3H, s), 1.59 (3H, d, J=7.0 Hz); MS (ESI) m/z 439 (M+H)+, 437 (M−H)−.

Provenance & Evidence